Environment and pharmaceuticals / Environmentally classified pharmaceuticals / D Dermatologicals

Environmentally classified pharmaceuticals

Two substances may have the same risk values but different PBT values, but the risk assessment can also be different even if the PBT values are the same. When assessing a medication's environmental impact, consideration should be given to both environmental risk and environmental hazard since bioaccumulation and persistence are not included in the risk assessment.

The Swedish Association of the Pharmaceutical Industry conducted the environmental risk assessment, beginning in 2005.

How to read the table

Last updated: 2011-08-19

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D Dermatologicals

Substance	Risk	PBT	P	B	T	Volume in DDD
D01 Antifungals for dermatological use
ketoconazole	low	9	3	3	3	4 540 E 2 400 900
miconazole	cannot be excl	9	3	3	3	76 E 2 786 680
terbinafine	cannot be excl	9 N.B.	3 N.B.	3	3	491 166 E 242 315
ekonazole	cannot be excl	-	-	-	-	E 3 455 350
bifonazole	cannot be excl	-	-	-	-	E 2 660
clotrimazole	cannot be excl	-	-	-	-	E 130 992
nystatin	cannot be excl	-	-	-	-	142 905
D02 Emollients and protectives
glycerin	exempt					C, E 78 806 124
urea	cannot be excl	3 N.B.	3 N.B.	0	0 N.B.	E 50 917 585
D04 Antipruritics, including antihistamines, anesthetics, etc
lidocaine	insigni- ficant	3	3	0	0	69 C, E 532 449
D05 Antipsoriatics
calcipotriol	cannot be excl	9 N.B.	3	3	3 N.B.	E 2 354 155
acitretin		9	3	3	3	54 685
D06 Antibiotics and chemotherapeutics for dermatological use
metronidazole	insigni- ficant	4	3	0	1	227 399 E 359 205
retapamulin	cannot be excl	5 N.B.	3	0	2 N.B.	E 19 355
penciclovir	insigni- ficant	3 N.B.	3	0	0 N.B.	E 10 808
aciclovir	insigni- ficant	4	3	0	1	123 079 E 1 952
fusidic acid	insigni- ficant	5	3	0	2	8 164 E 375 860
mupirocin	cannot be excl	3 N.B.	3 N.B.	0	0 N.B.	E 19 635
podophyllotoxin	cannot be excl	-	-	-	-	E 18 536
gentamicin	cannot be excl	6	3	0	3	10 414 E 30
oxytetracycline		6 N.B.	3 N.B.	0	3 N.B.	12 620 C, E 198 260
D07 Corticosteroids, dermatological preparations
hydrocortisone	cannot be excl	1 N.B.	0	0	1 N.B.	429 014 C, E 9 858 435
clobetasone	cannot be excl	9	3	3	3	E 481 325
betamethasone	cannot be excl	9 N.B.	3	3	3 N.B.	2 298 149 E 7 609 925
mometasone	cannot be excl	9 N.B.	3	3	3 N.B.	7 919 135 E 6 014 275
fusidic acid	insigni- ficant	5	3	0	2	8 164 E 375 860
clobetasol	insigni- ficant	9	3	3	3	E 1 790 150
salicylic acid	cannot be excl	4 N.B.	3 N.B.	0	1 N.B.	E 2 634 590
triamcinolone	cannot be excl	4 N.B.	3	0	1 N.B.	181 568 E 2 709 040
fluticasone	cannot be excl	6 N.B.	3	0	3 N.B.	1 768 857 E 3 372 380
fluocinolon	cannot be excl	-	-	-	-	E 28 110
D08 Antiseptics and disinfectants
chlorhexidine	low	9	3	3	3	E 130 062
D10 Anti-acne preparations
benzoyl peroxide	insigni- ficant	6	0	3	3	E 641 468
azelaic acid	cannot be excl	-	-	-	-	E 626 490
clindamycin	cannot be excl	6 N.B.	3	0	3 N.B.	232 401 E 715 981
tretinoin	cannot be excl	-	-	-	-	E 156 720
D11 Other dermatological preparations
finasteride	insigni- ficant	7	3	3	1	2 722 475
salicylic acid	cannot be excl	4 N.B.	3 N.B.	0	1 N.B.	E 2 634 590
pimecrolimus	cannot be excl	7 N.B.	3	3 N.B.	1 N.B.	E 17 955
minoxidil	cannot be excl	-	-	-	-	E 71 340
selenium sulfide	cannot be excl	-	-	-	-	E 205 920