Environment and pharmaceuticals / Environmentally classified pharmaceuticals / G Genito-urinary system and sex hormones

Environmentally classified pharmaceuticals

Two substances may have the same risk values but different PBT values, but the risk assessment can also be different even if the PBT values are the same. When assessing a medication's environmental impact, consideration should be given to both environmental risk and environmental hazard since bioaccumulation and persistence are not included in the risk assessment.

The Swedish Association of the Pharmaceutical Industry conducted the environmental risk assessment, beginning in 2005.

How to read the table

Last updated: 2011-05-11

« New search

G Genito-urinary system and sex hormones

Substance	Risk	PBT	P	B	T	Volume in DDD
G01 Gynecological anti-infectives and antiseptics
metronidazole	insigni- ficant	4	3	0	1	227 399 E 359 205
clindamycin	cannot be excl	6 N.B.	3	0	3 N.B.	232 401 E 715 981
clotrimazole	cannot be excl	-	-	-	-	E 130 992
econazole	cannot be excl	-	-	-	-	E 3 455 350
G02 Other gynecologicals
etonogestrel	insigni- ficant	8 N.B.	3	3	2 N.B.	3 946 000 E 2 229 696
ethinylestradiol	high	9	3	3	3	C 21 625 612 E 2 229 696
methylergometrine	cannot be excl	7 N.B.	3	3 N.B.	1 N.B.	15 109
atosiban	cannot be excl	-	-	-	-	390
dinoprostone	cannot be excl	-	-	-	-	9 814
cabergoline	cannot be excl	-	-	-	-	21 092
bromocriptine		9	3	3	3	148 534
gemeprost	cannot be excl	-	-	-	-	-
carboprost	cannot be excl	-	-	-	-	67
quinagolide	cannot be excl	-	-	-	-	56 481
G03 Sex hormones and modulators of the genital system
follitropin alfa	exempt					56 931
follitropin beta	exempt					72 244
corionic gonadotrophin	exempt					196 219
menotropin	exempt					132 575
urofollitropin	exempt					2 960
desogestrel	insigni- ficant	8	3	3	2	9 527 868 C 1 210 216
etonogestrel	insigni- ficant	8 N.B.	3	3	2 N.B.	3 946 000 E 2 229 696
ethinylestradiol	high	9	3	3	3	C 21 625 612 E 2 229 696
estradiol	moderate	9	3	3	3	6 109 337 C 3 209 075
estriol	cannot be excl	6 N.B.	3 N.B.	0	3 N.B.	1 845 840
norethisterone	cannot be excl	9	3	3	3	1 025 962 C 3 423 390
levonorgestrel	cannot be excl	9 N.B.	3	3	3 N.B.	6 514 C 10 545 360
ulipristal	cannot be excl	-	-	3	-	-
clomiphene	cannot be excl	-	-	-	-	198 766
medroxy- progesterone	cannot be excl	-	-	-	-	1 778 387 C 1 018 136
mifepristone	cannot be excl	-	-	-	-	2 708
progesterone	cannot be excl	-	-	-	-	E 1 232 277
drospirenone		8 N.B.	3	3 N.B.	2	C 4 837 672
dienogest	insigni- ficant	4	3	0	1	C 4 301
dydrogesterone	insigni- ficant	8	3	3	2	12 960
testosterone	cannot be excl	3	0	0	3	899 594
raloxifene	moderate	8	3	3	2	232 145
cyproterone	cannot be excl	9 N.B.	3	3	3 N.B.	27 809 C 661 332
lynestrenol	cannot be excl	-	-	-	-	1 185 700 K 76 188
norgestimate	cannot be excl	-	-	-	-	C 2 638 216
tibolone	cannot be excl	-	-	-	-	979 356
G04 Urologicals
sildenafil	insigni- ficant	2	0	0	2	499 936
alfuzosin	insigni- ficant	4 N.B.	3 N.B.	0	1	4 985 895
tadalafil	insigni- ficant	5	3	0	2	494 094
finasteride	insigni- ficant	7	3	3	1	2 722 475
tolterodine	cannot be excl	6 N.B.	3 N.B.	0	3 N.B.	1 313 877
solifenacin	cannot be excl	-	-	0	-	1 621 875
alprostadil	cannot be excl	-	-	-	-	156 062
fesoterodine	insigni- ficant	2 N.B.	0	0	2 N.B.	332 948
darifenacin	insigni- ficant	6	3	0	3	277 396
terazosin	cannot be excl	6 N.B.	3	0	3 N.B.	556 219
dutasteride	cannot be excl	8 N.B.	3	3	2 N.B.	1 043 850
vardenafil	cannot be excl	9 N.B.	3	3	3 N.B.	55 932
oxybutynin	cannot be excl	-	-	-	-	146 825