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Pharmaceuticals and Environment

Here you can find information about the environmental impact of pharmaceuticals. You can search for the substance name. Unless otherwise stated, the environmental impact means impact of pharmaceuticals when used.

Information about the classification

In a document there is information about the classification of the environmental hazard and the environmental risk. The classification of the risk is usually based on theoretical calculations of the risk. For more information see Classification.

For some substances there is also a risk assessment made on the basis of concentrations measured in the environment in Sweden and efficacy studies with high quality. These assessments are presented in the documents for the substances and are made by independent ecotoxicological expertise. Continuous work is underway to provide more substance documents with this type of environmental information and also present comparisons of environmental risk between substances intended for the same indication. Based on this type of risk assessment, a table of environmentally hazardous drugs Pdf, 41 kB. has been developed within the framework of Region Stockholm's environmental program 2017–2021.

News

Responsible Antibiotics Manufacturing Platform (RAMP)
SIWI
2021-12-16

Reithuber E, et al. THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates. PNAS November 23, 2021 118 (47) e2108244118. https://doi.org/10.1073/pnas.2108244118

Reported decrease in antibiotic consumption across EU/EEA during COVID-19 pandemic
European Centre for Disease Prevention and Control
2021-11-18

Antimicrobial consumption in the EU/EEA (ESAC-Net) - Annual Epidemiological Report for 2020
European Centre for Disease Prevention and Control
2021-11-18

World antimicrobial awareness week
WHO
18–24 November

OECD Health at a Glance 2021
2021-11-09

Larsson, D.G.J., Flach, CF. Antibiotic resistance in the environment. Nat Rev Microbiol (2021). https://doi.org/10.1038/s41579-021-00649-x

Edlund C, et al. The clinical and microbiological efficacy of temocillin versus cefotaxime in adults with febrile urinary tract infection, and its effects on the intestinal microbiota: a randomised multicentre clinical trial in Sweden. Lancet Infectious diseases. Published:October 28, 2021. DOI: https://doi.org/10.1016/S1473-3099(21)00407-2

Kanwischer M, et al. Substances of emerging concern in Baltic Sea water: Review on methodological advances for the environmental assessment and proposal for future monitoring. Ambio. 2021 Oct 12.
2021-10-27

Pharmaceuticals and endocrine disruptors: transfer from water to land ecosystems
European Commission
2021-10-14

Swedres-Svarm 2020. Sales of antibiotics and occurrence of
resistance in Sweden. Solna/Uppsala ISSN1650-6332.
2021-09-10

Möller V, et al. Antibiotic resistance among major pathogens compared to hospital treatment guidelines and antibiotic use in Nordic hospitals 2010–2018. Infectious diseases 2021, VOL. 53, NO. 8, 607–618.
2021-09-10

Use of antibiotics in animals is decreasing
EMA
2021-06-30

Cerveny D, Fick J, Klaminder J, et al. Water temperature affects the biotransformation and accumulation of a psychoactive pharmaceutical and its metabolite in aquatic organisms. Environment International, Volume 155, October 2021.

Cars O, Chandy SJ, Mpundu M, et al. Resetting the agenda for antibiotic resistance through a health systems perspective. Lancet Glob Health 2021; 9: e1022–27.

G7 ministers commit to combat antibiotic pollution from drug manufacturing.
University of Gothenburg
2021-06-09

S Svebrant, R Spörndly, RH Lindberg, et al. On-site pilot testing of hospital wastewater ozonation to reduce pharmaceutical residues and antibiotic-resistant bacteria. Antibiotics. 2021, 10(6), 684.

Nada H. Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy. Thesis for doctoral degree (Ph.D.). Karolinska Institutet 2021.

AS Bruun Rasmussen, A Hammou, T Fyhn Poulsen, et al. Definition, categorization, and environmental risk assessment of biopharmaceuticals. Science of The Total Environment
Volume 789, 1 October 2021, 147884.

ReAct Europe. Ensuring sustainable access to effective antibiotics for everyone ‒ everywhere. March 2021.

Vinterstare J. Defence on Demand. A physiological perspective on phenotypic plasticity in anti-predator traits. Lund University. Doctoral dissertation. 2021. ISBN 978-91-7895-756-9

Kraupner N, Hutinel M, Schumacher K, et al. Evidence for selection of multi-resistant E. coli by hospital effluent.Environment International Volume 150, May 2021, 106436. https://doi.org/10.1016/j.envint.2021.106436

Pinheiro, F., Warsi, O., Andersson, D.I. et al. Metabolic fitness landscapes predict the evolution of antibiotic resistance. Nat Ecol Evol (2021). https://doi.org/10.1038/s41559-021-01397-0

Antibiotics: even low levels found in the environment might drive resistance
European Commission
2021-03-03

Waste water treatment pains
Svenskt Vatten
2021-03-01

Engelsk flagga

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