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Pharmaceuticals and Environment

Maintenance work 2020-09-11: Work is underway to remove the hazard score, i.e. the numerical values for P, B and T. Instead, information on persistence, bioaccumulation, toxicity and risk will be described in text including underlying data. You can to search the database as before during this work.

Here you can find information about the environmental impact of pharmaceuticals. You can search for the substance name. Unless otherwise stated, the environmental impact means impact of pharmaceuticals when used.

Information about the classification

In the document there is information about the classification of the environmental hazard and the environmental risk. The text may indicate if T refers to acute or chronic toxicity. The environmental hazard is classified from 0–9, where a high number indicates high properties for making an environmental impact. The classification of the risk is usually based on theoretical calculations of the risk. For more information see Classification.

For some substances there is also a risk assessment made on the basis of concentrations measured in the environment in Sweden and efficacy studies with high quality. These assessments are presented in the documents for the substances and are made by independent ecotoxicological expertise. Continuous work is underway to provide more substance documents with this type of environmental information and also present comparisons of environmental risk between substances intended for the same indication. Based on this type of risk assessment, a table of environmentally hazardous drugs has been developed within the framework of Stockholm County Council's environmental program 2017–2021.

News

2020

Näslund J, Asker N, Fick J, Larsson J, Norrgren L. Naproxen affects multiple organs in fish but is still an environmentally better alternative to diclofenac. Aquatic Toxicology, Volume 227, October 2020. https://doi.org/10.1016/j.aquatox.2020.105583

Fahlman J. The fate and effect of pharmaceuticals in boreal surface waters. Dissertation for PhD. Department of Ecology and Environmental Science Umeå 2020.
2020-09-01

Reducing emissions from antibiotic production
SIWI
2020-07-02

Faisal Ahmad Khan. Carbapenemase-producing Enterobacteriaceae in wastewater-associated aquatic environments. Doctoral dissertation 2020. ISBN 978-91-7529-334-9.

Ramström, H., Martini, S., Borgendahl, J. et al. Pharmaceuticals and Environment: a web-based decision support for considering environmental aspects of medicines in use. Eur J Clin Pharmacol (2020). https://doi.org/10.1007/s00228-020-02885-1
2020-05-10

The health paradox. Report #96.
Swedwatch
2020-02-19

Rutgersson C, Ebmeyer S, Lassen SB, Karkman A, Fick J, Kristiansson E, Brandt KK, Flach C-F, Larsson DGJ. Long-term application of Swedish sewage sludge on farmland does not cause clear changes in the soil bacterial resistome. Environmental International 137 (2020) 105339. https://doi.org/10.1016/j.envint.2019.105339
2020-02-10

Nijsingh N, Munthe C and Larsson DGJ. Managing pollution from antibiotics manufacturing: charting actors, incentives and disincentives. Environmental Health (2019) 18:95 https://doi.org/10.1186/s12940-019-0531-1.
2020-01-20

Tepper V, Nykvist M, Gillman A, Skog E, Wille M, Lindström HS, Tang C, Lindberg RH, Lundkvist Å, Järhult JD. Influenza A/H4N2 mallard infection experiments further indicate zanamivir as less prone to induce environmental resistance development than oseltamivir. J Gen Virol. 2019 Dec 19. doi: 10.1099/jgv.0.001369.
2020-01-07

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